Although many people think of varicose veins as a nuisance or a cosmetic defect, the manifestation of varicose and spider veins is a sign that the circulatory system in the legs is not performing adequately. Lifestyle, diet, adequate exercise and maintaining a healthy weight are important factors in ensuring vein and circulatory system health. Nutritional strategies that help address varicose veins include nutrients that help improve vein structural integrity and vein tissue healing; reduce inflammation; and improve overall circulatory system health, including leg circulation.

Diosmin, a naturally-occurring flavonoid found in citrus rinds, has been shown to improve venous tone and shorten vein healing times. (Bergan et al. 2001; Le Devehat et al. 1997; Ramlet 2001) Several studies have investigated the effects of Horse Chestnut extract in venous insufficiency and have shown an improvement in those treated. (Greesek et al. 1996; Pittler and Ernst 2002; Seibert et al. 2002; Simini 1996) Gotu Kola extract (Centella asiatica) supports connective tissue health, which has some beneficial effects on vein health. (Allegra 1981; Tenni et al. 1988)

Nutrients that display anti-inflammatory and antioxidant action designed to promote tissue healing include Diosmin, which acts as an anti-inflammatory by inhibiting prostaglandin E2 and thromboxane A2 (Smith 1999) and exhibits free radical scavenging activity. (Thorne 2004) Horse Chestnut extract has potent antioxidant and anti-inflammatory activity. (Guillaume et al. 1994) Research on the components of Gotu Kola extract has shown potent anti-inflammatory activity (Somchit et al. 2004) and antioxidant activity. (Gupta et al. 2003) Citrus Bioflavonoids have anti-inflammatory effects that make them useful in treating varicose veins. (Galati et al. 1994; Menkin 1995)

Nutrients that have been shown to help improve overall circulatory system health include Diosmin, which protects capillary bed microcirculation, increases lymphatic drainage and protects against microcirculatory damage. (Bergan 2001; Manthey 2000) Horse Chestnut works to improve venous insufficiency by decreasing capillary leakage and permeability and improving overall circulatory system health. (Guillaume et al. 1994) Gotu Kola and Butcher's Broom have been found to be useful in enhancing both vein and capillary health and promoting a healthy circulatory system. (Cesarone et al. 1994; DeSanctis et al. 1994)